| Day | Date | Opponent | Location | TV | Outcome/Time |
| Fri | 11/03/2000 | Basketball Travelers (Exh.) | College Park, Md. | | W, 110-77
Recap | Stats |
| Wed | 11/15/2000 | EA Sports/California All-Stars (Exh.) | College Park, Md. | | W, 91-55
Recap | Stats | Archived Audio |
| Mon | 11/20/2000 | Louisville (Maui Invitational) | Lahaina, Hawaii | ESPN2 | W, 95-73
Recap | Stats |
| Tue | 11/21/2000 | Illinois | Lahaina, Hawaii
(Maui Invitational) | ESPN | L, 90-80
Recap | Stats | Archived Audio |
| Wed | 11/22/2000 | Dayton | Lahaina, Hawaii
(Maui Invitational) | | L, 77-71
Recap | Stats | Archived Audio |
| Wed | 11/29/2000 | Wisconsin (ACC/Big Ten Challenge) | Milwaukee | ESPN | L, 78-75 (OT)
Recap | Stats | Archived Audio |
| Sat | 12/02/2000 | Michigan (BB&T Classic) | Washington, D.C.
(MCI Center) | Raycom | W, 82-51
Recap | Stats | Archived Audio |
| Sun | 12/03/2000 | George Washington | Washington, D.C.
(MCI Center) | Raycom | W, 71-63
Recap | Stats | Notes | Archived Audio |
| Wed | 12/06/2000 | Stony Brook | College Park, Md. | | W, 107-59
Recap | Stats | Quotes | Notes | Archived Audio |
| Sat | 12/09/2000 | Pennsylvania | Philadelphia | HTS-Comcast | W, 87-81
Recap | Stats | Archived Audio |
| Wed | 12/13/2000 | Maryland-Baltimore County | College Park, Md. | | W, 93-67
Recap | Stats | Notes and Quotes | Archived Audio |
| Sat | 12/23/2000 | Norfolk State | College Park, Md. | HTS | W, 123-78
Recap | Stats | Quotes | Archived Audio |
| Wed | 12/27/2000 | Chicago State | College Park, Md. | | W, 117-55
Recap | Stats | Quotes | Notes | Archived Audio |
| Sat | 12/30/2000 | UMES | College Park, Md. | HTS | W, 105-53
Recap | Stats | Quotes | Notes | Archived Audio |
| Tue | 01/02/2001 | o Clemson | Clemson, S.C. | RJ | W, 104-92
Recap | Stats | Archived Audio |
| Sat | 01/06/2001 | o Georgia Tech | College Park, Md. | RJ | W, 93-80
Recap | Stats | Quotes | Notes | Archived Audio |
| Wed | 01/10/2001 | o North Carolina | College Park, Md. | ESPN | L, 86-83
Recap | Stats | Quotes | Notes | Archived Audio |
| Sun | 01/14/2001 | o Florida State | Tallahassee, Fla. | RJ | W, 76-55
Recap | Stats | Archived Audio |
| Wed | 01/17/2001 | o Wake Forest | College Park, Md. | ESPN | W, 81-71
Recap | Stats | Quotes | Notes | Archived Audio |
| Sun | 01/21/2001 | o NC State | Raleigh, N.C. | ABC | W, 75-61
Recap | Stats | Archived Audio |
| Sat | 01/27/2001 | o Duke | College Park, Md. | ESPN | L, 98-96 (ot)
Recap | Stats | Quotes | Notes | Archived Audio | FANSlive GameTracker |
| Wed | 01/31/2001 | o Virginia | Charlottesville, Va. | ESPN | L, 99-78
Recap | Stats | Archived Audio |
| Sun | 02/04/2001 | o Clemson | College Park, Md. | RJ | W, 69-54
Recap | Stats | Quotes | Notes | Archived Audio | FANSlive GameTracker |
| Tue | 02/06/2001 | o Georgia Tech | Atlanta | FSS-HTS-SUN | L, 72-62
Recap | Stats | Archived Audio |
| Sat | 02/10/2001 | o North Carolina | Chapel Hill, N.C. | CBS | L, 96-82
Recap | Stats | Archived Audio |
| Wed | 02/14/2001 | o Florida State | College Park, Md. | RJ | L, 74-71
Recap | Stats | Quotes | Notes | Archived Audio | FANSlive GameTracker |
| Sat | 02/17/2001 | o Wake Forest | Winston-Salem, N.C. | RJ | W, 73-56
Recap | Stats | Archived Audio |
| Tue | 02/20/2001 | o NC State | College Park, Md. | RJ-ESPN2 | W, 95-66
Recap | Stats | Quotes | Notes | Archived Audio | FANSlive GameTracker |
| Sat | 02/24/2001 | Oklahoma | College Park, Md. | ABC | W, 68-60
Recap | Stats | Quotes | Notes | Archived Audio | FANSlive GameTracker |
| Tue | 02/27/2001 | o Duke | Durham, N.C. | RJ | W, 91-80
Recap | Stats | Archived Audio |
| Sat | 03/03/2001 | o Virginia | College Park, Md. | CBS | W, 102-67
Recap | Stats | Quotes | Notes | Archived Audio | FANSlive GameTracker |
| Fri | 03/09/2001 | Wake Forest (1st Round ACC Tournament) | Atlanta | RJ | W, 71-53
Recap | Stats | Quotes | Notes | Archived Audio | FANSlive GameTracker |
| Sat | 03/10/2001 | Duke (ACC Tournament Semifinal) | Atlanta | RJ-ESPN | L, 84-82
Recap | Stats | Quotes | Archived Audio | FANSlive GameTracker |
| Thu | 03/15/2001 | George Mason (NCAA First Round) | Boise, Idaho | CBS | W, 83-80
Recap | Stats | Archived Audio | FANSlive GameTracker |
| Sat | 03/17/2001 | Georgia State (NCAA Second Round) | Boise, Idaho | CBS | W, 79-60
Recap | Stats | Archived Audio | FANSlive GameTracker |
| Thu | 03/22/2001 | Georgetown | Anaheim, Calif.
(NCAA Sweet 16) | CBS | W, 76-66
Recap | Stats | Archived Audio | FANSlive GameTracker |
| Sat | 03/24/2001 | Stanford | Anaheim, Calif.
(NCAA Regional Final) | CBS | W, 87-73
Recap | Stats | Archived Audio | FANSlive GameTracker |
| Sat | 03/31/2001 | Duke | Minneapolis | CBS | L, 95-84
Recap | Stats | Archived Audio | FANSlive GameTracker |
